Acute generalized exanthematous pustulosis induced by terbinafine: a case report.

Authors

  • Helberth José Cuchía
  • Néstor Fernando Arévalo
  • Héctor José Castellanos

Keywords:

Acute generalized exanthematous pustulosis,, adverse cutaneous drug reaction, pustular eruption

Abstract

Acute generalized exanthematous pustulosis (AGEP) is an uncommon, generalized aseptic pustular eruption, which is manifestation in over 90% of the cases of an adverse drugs reaction. More than 50% of the responsible drugs are antibacterial agents and the antimycotics accounted for about 10%, with terbinafine heading this list.

Author Biographies

Helberth José Cuchía

Médico Residente 2do. Año de Dermatología, Universidad Nacional de Colombia, Bogotá D.C.

Néstor Fernando Arévalo

Médico Dermatólogo, Clínica Carlos Lleras Restrepo, Bogotá D.C.

Héctor José Castellanos

Médico Dermatólogo, Hospital Universitario de la Samaritana. Docente, Universidad Nacional de Colombia, Bogotá D.C.

References

1. Beltraminelli HS, Lerch M, Arnold A, Bircher AJ, Haeusermann P. Acute generalized exanthematous pustulosis induced by the antifungal terbinafine: case report and review of the literature. Br J Dermatol. 2005;152:780-3.
2. Bachot N, Roujeau JC. Differential Diagnosis of Severe Cutaneous Drug Eruptions. Am J Clin Dermatol 2003; 4: 561-72.
3. McKenna JK, Leiferman KM. Dermatologic drug reactions. Immunol Allergy Clin N Am 2004 ; 24: 399–423.
4. Knowles SR, Shear NH. Recognition and Management of Severe Cutaneous Drug Reactions. Dermatol Clin 2007; 25:245–53.
5. Sidoroff A, Halevy S, Bavinck JN, Vaillant L, Roujeau JC. Acute generalized exanthematous pustulosis (AGEP) – a clinical reaction pattern. J Cutan Pathol 2001; 28:113–9.
6. Leonard N. New entities in dermatopathology. Current Diagnostic Pathology 2005; 11: 253-63.
7. Lombardo M, Cerati M, Pazzaglia A. Acute generalized exanthematous pustulosis induced by terbinafine. J Am Acad Dermatol. 2003; 49:158-9.

How to Cite

1.
Cuchía HJ, Arévalo NF, Castellanos HJ. Acute generalized exanthematous pustulosis induced by terbinafine: a case report. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 6 [cited 2026 Mar. 19];16(3):214-6. Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/118

Downloads

Download data is not yet available.

Published

2019-02-06

How to Cite

1.
Cuchía HJ, Arévalo NF, Castellanos HJ. Acute generalized exanthematous pustulosis induced by terbinafine: a case report. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 6 [cited 2026 Mar. 19];16(3):214-6. Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/118
Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views