Nodular prurigo as a paraneoplastic manifestation of mediastinal Hodgkin lymphoma
DOI:
https://doi.org/10.29176/2590843X.1633Keywords:
Hodgkin lymphoma, Metastatic tumor’s, Paraneoplastic syndrome, PrurigoAbstract
Introduction: prurigo nodularis is a very pruritic chronic dermatosis, characterized by the appearance of hyperkeratotic skin nodules in middle-aged adults. Sometimes it can be the initial manifestation of a lymphoproliferative disease.
Objective: to present the case of a patient with a history of prurigo nodularis as a paraneoplastic manifestation of a mediastinal hodgking lymphoma.
Case presentation: 48-year-old patient with a history of prurigo nodularis. Three years after diagnosis, she presented an increase in volume of the anterior region of the thorax. In the imaging studies, a tumor of the anterosuperior mediastinum was demonstrated, which was concluded in the histological study as a variant Hodgkin's lymphoma nodular sclerosis.
Conclusions: chronic skin lesions can be manifestations of internal neoplasms.
Author Biographies
Miguel Emilio García Rodríguez, Hospital Universitario General Calixto García. Servicio de Cirugía General,Hospital Universitario General Calixto García. Servicio de Cirugía General
Doctor en Medicina. Doctor en Ciencias Médicas. Especialista de Segundo Grado en Cirugía General. Especialista de Segundo Grado en Organización y Administración de Salud. Máster en Urgencias Médicas. Profesor e Investigador Titular. Universidad de Ciencias Médicas de la Habana. Hospital Universitario General Calixto García. Servicio de Cirugía General, Camagüey, Cuba.
Miguel Javier García-Basulto, Instituto de Cardiología y Cirugía Cardiovascular
Doctor en Medicina. Residente de quinto año de Cirugía Cardiovascular. Universidad de Ciencias Médicas de la Habana. Instituto de Cardiología y Cirugía Cardiovascular. Servicio de Cirugía Cardiovascular, La Habana, Cuba.
Arián Benavidez Márquez, Hospital Universitario Manuel Ascunce Domenech. Servicio de Anestesiología y Reanimación
Doctor en Medicina. Especialista de Primer Grado en Anestesiología y Reanimación. Asistente. Universidad de Ciencias Médicas de Camagüey. Hospital Universitario Manuel Ascunce Domenech. Servicio de Anestesiología y Reanimación, Camagüey, Cuba.
References
Huang A H, Williams K A, Kwatra S G. (2020). Prurigo nodularis: Epidemiology and clinical features. Journal of the American Academy of Dermatology, 83(6), 1559–1565. https://doi.org/10.1016/j.jaad.2020.04.183
Didona D, Fania L, Didona B, Eming R, Hertl M, Di Zenzo G. (2020). Paraneoplastic Dermatoses: A Brief General Review and an Extensive Analysis of Paraneoplastic Pemphigus and Paraneoplastic Dermatomyositis. International journal of molecular sciences, 21(6), 2178. https://doi.org/10.3390/ijms21062178
Serra-Garcia L, Riera-Monroig J, Riquelme-Mc Loughlin C, Morgado-Carrasco Daniel C. (2021). Chronic prurigo as a onset of Hodgkin's lymphoma. Medicina clinica, 156(1), 47. https://doi.org/10.1016/j.medcli.2019.10.004
Zeidler C, Tsianakas A, Pereira M, Stander H, Yosipovitch G, Stander S. Chronic Prurigo of Nodular Type: A Review. Acta Derm Venereol. 2018; 98(2):173-9. https://www.ncbi.nlm.nih.gov/pubmed/29135018
Pereira MP, Stander S. How to define chronic prurigo? Exp Dermatol. 2019;28(12):1455-60. https://www.ncbi.nlm.nih.gov/pubmed/31102542
Redondo-Sendino Á, Gil-Muñoz MC, Redondo-Sendino JI. Prurigo nodular, un reto terapéutico. Medicina de Familia SEMERGEN. 2020; 46(8):e70-e1. https://doi.org/10.1016/j.semerg.2020.05.016
Williams K A, Roh YS, Brown I, Sutaria N, Bakhshi P, Choi J, et al. (2021). Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis. Expert review of clinical pharmacology, 14(1), 67–77. https://doi.org/10.1080/17512433.2021.1852080
Dumont S, Péchère M, Toutous Trellu L. (2018). Chronic Prurigo: An Unusual Presentation of Hodgkin Lymphoma. Case reports in dermatology, 10(2), 122–126. https://doi.org/10.1159/000489161
Tsianakas A, Zeidler C, Stander S. Prurigo Nodularis Management. Curr Probl Dermatol. 2016; 50:94-101. https://www.ncbi.nlm.nih.gov/pubmed/27578077
Alonso C, Dutta SW, Mitra N, Landsburg DJ, Zaorsky NG, Grover S, et al. Adult nodular lymphocyte-predominant Hodgkin lymphoma: treatment modality utilization and survival. Cancer Med. 2018; 7(4):1118-26. https://www.ncbi.nlm.nih.gov/pubmed/29479868
How to Cite
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Miguel Emilio García Rodríguez, Miguel Javier García-Basulto, Arián Benavidez Márquez
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
