DRESS syndrome associated with the use of Linezolid
DOI:
https://doi.org/10.29176/2590843X.1765Keywords:
Linezolid, acute kidney injury, acute interstitial nephritis, rug rash with eosinophilia and systemic symptoms (DRESS) syndrome, eosinophiliaAbstract
Drug reactions occur in 10 to 20% of hospital admissions, and in 10% of cases they may correspond to serious drug reactions. DRESS represents around 15% of all adverse skin reactions to drugs; the risk of developing it varies from one drug to another, approximately in 80% of cases a clear trigger can be identified. However, in the remaining 10 to 20%, the strength of drug causation is less clear, and in 2% of cases, there is no drug exposure. A large proportion of cases (approximately 75%) are due to some high-risk medications, including aromatic anticonvulsants, allopurinol, and some antibacterial agents such as sulfonamides. Recently, cases of DRESS syndrome secondary to the use of antimicrobial treatments less commonly associated with this type of complications such as Linezolid, which is well tolerated by most patients, have been described. We present the case of a patient with baseline obesity who presented DRESS Syndrome after starting Linezolid.
Author Biographies
María Fernanda Velasco Hoyos, Hospital Universitario de Neiva
Médica internista, Universidad Surcolombiana, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia.
Germán Giraldo-Bahamón, Hospital Universitario de Neiva
Médico internista, Universidad Surcolombiana, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia.
Álvaro Díaz, Hospital Universitario de Neiva
Dermatólogo, Universidad Surcolombiana, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia.
Diego Pérez-Covo, Hospital Universitario de Neiva
Residente de Medicina Interna, Universidad Surcolombiana, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia.
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Copyright (c) 2024 María Fernanda Velasco Hoyos, Germán Giraldo-Bahamón, Álvaro Díaz, Diego Pérez-Covo
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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