Atypical fibroxanthoma versus pleomorphic dermal sarcoma
DOI:
https://doi.org/10.29176/2590843X.1797Keywords:
Atypical fibroxanthoma, Pleomorphic sarcoma, Scalp, Skin neoplasmAbstract
Atypical fibroxanthoma (FXA) is a little-known superficial mesenchymal tumor that generally occurs in photoex posed areas of older adults (1). It has an intermediate degree of malignancy due to its capacity for recurrence, and it is estimated that it comprises up to 0.2% of skin tumors (2). It has very similar histological features to undiffer entiated pleomorphic sarcoma, a high-grade, aggressive tumor with a poor prognosis. Subtle aspects, such as the clinical history and location of the lesion, are key to a more accurate diagnosis.
The case report describes an elderly patient with a scalp lesion and diagnosis of “vascular malformation” without further clinical information, which made the diagnosis and differentiation between these two entities difficult,
Author Biographies
Sara Manuela Gil Hernandez, Grupo medicina personalizada - Ayudas Diagnosticas Sura
Physician, pathologist at Ayudas Diagnósticas Sura. Member of the molecular cytopathology line of the personalized medicine research group of the Research and Development Directorate for South Colombia.
Alfredo Martelo, Ayudas Diagnósticas SURA
Patólogo, Ayudas Diagnósticas SURA, Medellín, Colombia.
Juan Eduardo Rocha, Universidad CES
Dermatopatólogo. Docente de Dermatología, Universidad CES, Medellín, Colombia.
Melisa Sofía Naranjo Vanegas, Ayudas Diagnósticas SURA, Medellín, Colombia
Médica. Magíster en Epidemiología y Salud Pública, Grupo de Investigación en Imágenes Médicas e IA. Gerencia de Biociencias, Ayudas Diagnósticas SURA, Medellín, Colombia.
References
Jara, Natalia & Solé Z, Sebastián (2019). Fibroxantoma atípico. Caso clínico. Revista médica de Chile, 147(10), 1346-1349.
http://dx.doi.org/10.4067/s0034-98872019001001346
Koch M, Freundl AJ, Agaimy A, Kiessewetter F, Künzel J, Cicha I, et al.
Atypical Fibroxanthoma – Histological diagnosis, immunohistochemical markers and concepts of therapy. Anticancer Res. 2015; 35:5717-35
Villanueva, DV, Hisas, M, Scarso, A Rodriguez, Paiva, C, & Pérez, G. (2021). Fibroxantoma atípico. Revista argentina de dermatología, 102(2), 71-80.
Calvo Archanco I, Del Castillo Pardo de Verda JL, Losa Muñoz PM. Fibroxantoma Atípico. Rev Española Cir Oral Maxiofac 2017: 39(4): 245-252
Ziemer M. Atypical fibroxanthoma. JDtsch Dermal Ges. 2012;10:537-48.
Brenn T. Pleomorphic dermal neoplasms: A reviw. Adv Anat Pathol. 2014;21:108-30.
Rios Vinuela E, Serra- Guillen C, Llombart B, Requena C, Nagore E, et al. (2020) Pleomorphic dermal sarcoma: a retrospective study of 16 cases in a dermato-oncology centre and a reviw of the literatura. Eur J Dermal 30(5): 545-553.
Love WE, Schimitt AR, Bordeux JS. Management of unusual cutaneous malignancies: Atypical fibroxanthoma, malignant fibrous histiocytoma, sebaceous carcinoma, extrammary paget disease. Dermatol Clin. 2011, 29:201-16.
Ang GC, Roenigk RK, Otley CC, Phillips KP, Weaver AL. More tan 2 decadesof treating atypical fibroxanthoma ay mayo clinic: What have we learned from 91 patients? Dermatol surg. 2009; 35:765-72
How to Cite
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Sara Manuela Gil Hernandez, Alfredo Martelo, Juan Eduardo Rocha, Melisa Sofía Naranjo Vanegas
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
