Acute generalized Von Zumbuch pustular psoriasis, de novo case, associated with hypocalcemia
DOI:
https://doi.org/10.29176/2590843X.1932Keywords:
pustular psoriasis, hypocalcemia, hypoparathyroidism.Abstract
Von Zumbusch pustular psoriasis is a severe form of generalized psoriasis, which has the characteristic presentation of sterile pustules with an erythematous base, associated with systemic manifestations. A female patient, 53 years old, with a history of primary hypoparathyroidism, denies psoriasis, is described; I presented periumbilical pruritic pustules on the palms and soles, which subsequently generalized abruptly, after 7 days due to persisting symptoms and adding thermal rise, myalgias and arthralgias to the clinical picture, come to our service. Evidence of generalized dermatosis characterized by erythematous plaques, with yellow pustules on the non-foul, pruritic surface of weeks of evolution. Laboratory tests showed elevated levels of leukocytes, C-reactive protein, ESR, LDH, and the presence of hypocalcemia. A skin biopsy was performed in association with Von Zumbuch's acute generalized pustular psoriasis. Treatment was indicated with Syndet, emollients, calcium carbonate 1500 mg every 12 hours, methotrexate 15 mg vs. weekly. With good response.
Author Biographies
Mary Lisbeth Soto-Pernia, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Valencia, Venezuela
Médico residente, tercer año del postgrado de Dermatología, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Valencia, Venezuela.
María Manzanero, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Venezuela
Médico residente, tercer año del postgrado de Dermatología, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Venezuela.
Ismar Marte, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Venezuela
Médica y dermatóloga, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Venezuela.
Sandra Carlina Vivas Toro, Universidad de Carabobo, Ciudad Hospitalaria “Dr. Enrique Tejera”, Valencia, Estado Carabobo, Venezuela.
Médica internista y dermatóloga. Magíster en Investigación Educativa. Jefa, Servicio de Dermatología, Universidad de Carabobo de La Ciudad Hospitalaria “Dr. Enrique Tejera”. Coordinadora, Programa de Postgrado de Dermatología.
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Copyright (c) 2025 Mary Lisbeth Soto-Pernia, María Manzanero, Ismar Marte, Sandra Carlina Vivas Toro
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