Acute generalized exanthematous pustulosis in a young patient
DOI:
https://doi.org/10.29176/2590843X.1951Keywords:
Acute generalized exanthematous pustulosis, Drug-induced reactions, Pustular skin eruptions, Severe adverse skin reactionsAbstract
Acute generalized exanthematous pustulosis (AGEP) is a rare dermatological pathology, characterized by the sudden appearance of skin lesions in the form of multiple, punctate, sterile pustules, on an edematous erythematous background. It has generally been associated with multiple drugs, including exposure to certain antibiotics. We present the case of a 34-year-old male patient who was admitted to the emergency department due to the appearance of pustular lesions of two weeks' duration, pruritic, some ulcerated, with signs of superinfection, which involved the four extremities, genitals, anterior and posterior trunk, respecting mucous membranes. Admission tests showed a leukemoid reaction with a leukocyte count of 83,000 cells/mL, predominance of neutrophils (75,250 cells/mL) with eosinophilia of 2,520 cells/mL and elevated C-reactive protein (CRP) (29.2 mg/dL). In the skin biopsy, they reported changes suggestive of PEGA, with improvement and resolution of the inflammatory skin manifestations after treatment with systemic steroids.
Author Biographies
Ahmad Talat Ahmad Kanan, Universidad Libre de Colombia
Médico residente de Medicina Interna, Universidad Libre, Seccional Cali. Grupo Interinstitucional de Medicina Interna (GIMI1), Universidad Libre, Seccional Cali, Colombia.
Martín Ocampo, Pontifical Xavierian University
Médico internista, Clínica Versalles, Cali, Colombia. Grupo de Investigación en Ciencias Básicas y Clínicas de la Salud, Universidad Javeriana, Cali, Colombia.
Abdel Halim Ibrahim-Méndez, Clínica Versalles
Médico dermatólogo, Clínica Versalles, Cali, Colombia.
Isabella Calle, Pontifical Xavierian University
Estudiante, pregrado de Medicina, Pontificia Universidad Javeriana.
References
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Copyright (c) 2025 Ahmad Talat Ahmad Kanan, Martín Ocampo, Abdel Halim Ibrahim-Méndez, Isabella Calle
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