From andean ancestors to precision immunotherapy: evolution and revolution of systemic therapies in oncologic dermatology

Authors

DOI:

https://doi.org/10.29176/2590843X.2194

Keywords:

melanoma

Abstract

Desde los primeros registros
precolombinos hasta las terapias
celulares personalizadas, la
dermatología oncológica ha
recorrido un camino extraordinario.

Author Biographies

Melanie Alejandra Villamizar Téllez, Universidad Nacional de Colombia, Bogotá, Colombia

Médica general, Universidad Nacional de Colombia. Coordinadora, Grupo de Interés en Dermatología, UN-DERMIG

Héctor Camilo Pérez Cely, Universidad Militar Nueva Granada, Bogotá, Colombia

Dermatólogo oncólogo. Profesor asistente, Universidad Nacional de Colombia. Profesor honorario, Universidad Militar Nueva Granada.

References

Sekulic A, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med. 2012;366(23):2171–2179. https://doi.org/10.1056/NEJMoa1113713

Migden MR, et al. PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma. N Engl J Med. 2018;379(4):341–351. https://doi.org/10.1056/NEJMoa1805131

Hodi FS, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711–723. https://doi.org/10.1056/NEJMoa1003466

Larkin J, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. N Engl J Med. 2015;373(1):23–34. https://doi.org/10.1056/NEJMoa1504030

Chapman PB, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364(26):2507–2516. https://doi.org/10.1056/NEJMoa1103782

Morton DL, et al. Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med. 2006;355(13):1307–1317. https://doi.org/10.1056/NEJMoa060992

Weber J, et al. Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma. N Engl J Med. 2017;377(19):1824–1835. https://doi.org/10.1056/NEJMoa1709030

Eggermont AMM, et al. Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma. N Engl J Med. 2018;378(19):1789–1801. https://doi.org/10.1056/NEJMoa1802357

Reijers ILM, et al. Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial. Nat Med. 2022;28(6):1178–1188. https://doi.org/10.1038/s41591-022-01851-x

Blank CU, et al. Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma. N Engl J Med. 2024;391(18):1696–1708. https://doi.org/10.1056/NEJMoa2402604

How to Cite

1.
Villamizar Téllez MA, Pérez Cely HC. From andean ancestors to precision immunotherapy: evolution and revolution of systemic therapies in oncologic dermatology. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2025 Dec. 1 [cited 2026 Mar. 19];33(4). Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/2194

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Published

2025-12-01

How to Cite

1.
Villamizar Téllez MA, Pérez Cely HC. From andean ancestors to precision immunotherapy: evolution and revolution of systemic therapies in oncologic dermatology. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2025 Dec. 1 [cited 2026 Mar. 19];33(4). Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/2194
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