Hydroa vacciniforme and hydroa vacciniforme-like lymphoproliferative disorder: a case report and literature review
DOI:
https://doi.org/10.29176/2590843X.1840Keywords:
hydroa vacciniforme, Lymphoma, EBV, hydroa vacciniforme-like lymphoma, hydroa vacciniforme-like lymphoproliferative disorderAbstract
Introduction: Hydroa vacciniforme is an uncommon photodermatosis that causes chronic skin involvement and might be related to the Epstein-Barr virus infection, associating progressive cicatricial deformity and a higher risk of developing cutaneous lymphomas.
Method: This is a descriptive observational type of study. Therefore, it details a rare photodermatosis in a male pediatric patient with a history of Epstein Barr virus exposure, who presented blisters and chronic ulcers in photoexposed areas.
Results: A 13-year-old boy suffering from deforming chronic ulcers in the face and ears, whose histopathological study revealed a marked lymphocytic infiltrate with angiocentrism, suggesting hydroa vacciniforme. Yet positive markers of cutaneous lymphoma associated with Epstein Barr virus were identified by immunohistochemistry.
Conclusion: This article reports a pediatric hydroa vacciniforme-like lymphoproliferative disorder case without systemic involvement, associated with Epstein-Barr virus exposure. Indeed, it is an unusual case in which histological and immunohistochemical pattern is aggressive and in whom the prognosis is still unknown
Author Biographies
Ana María Gutiérrez-Delgadillo, Universidad El Bosque
Dermatóloga, Universidad El Bosque, Bogotá, Colombia
Johanna Villamil Guevara, El Bosque University
Dermatóloga, Universidad El Bosque, Bogotá, Colombia
Nelson Ricardo Porras Sánchez, El Bosque University
Dermatólogo, Universidad El Bosque, Bogotá, Colombia
Valentina Pastrana-Tovar, El Bosque University
Oftalmóloga, Universidad El Bosque, Bogotá, Colombia
Elvia Zenaida Quevedo-Martínez, El Bosque University
Dermatóloga, Universidad El Bosque, Bogotá, Colombia
Mariam Carolina Rolón-Cadena, Universidad El Bosque
Dermatopatóloga, Universidad El Bosque, Bogotá, Colombia.
Adriana Motta-Beltrán, El Bosque University
Dermatóloga, Hospital Simón Bolívar. Universidad El Bosque, Bogotá, Colombia
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Copyright (c) 2024 Ana María Gutiérrez-Delgadillo, Johanna Villamil Guevara, Nelson Ricardo Porras Sánchez, Valentina Pastrana-Tovar, Elvia Zenaida Quevedo-Martínez, Mariam Carolina Rolón-Cadena, Adriana Motta-Beltrán
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