Blastic plasmocytoid dendritic cell neoplasm: a diagnostic challenge
DOI:
https://doi.org/10.29176/2590843X.1783Keywords:
CD56 antigen, Dendritic cells, Leukemia myeloid, Neoplasms, Plasmacytoid dendritic cellsAbstract
Blastic plasmacytoid dendritic cell neoplasm is a very rare tumor that represents less than 1% of all hematopoietic malignancies; with high skin involvement and risk of leukemic dissemination, as well as aggressive behavior with a median survival of 14 months and a relapse rate of 17-33%. The diagnosis must be determined histologically and immunophenotypically by checking the positivity mainly of CD4 and CD56, in the absence of other specific lineage markers. This tumor has been associated with a history of myelodysplastic syndrome and myeloproliferative neoplasms; however, to date it is the first reported case of the association of a patient with pharmacological immunosuppression and this type of tumor as a possible risk factor.
Author Biographies
Katty Camila Anaya Reyes, Universidad Autonoma de Bucaramanga
Residente de Dermatología, Universidad Autónoma de Bucaramanga.
Español Español, Foscal Internacional, Floridablanca, Santander, Colombia
Dermatóloga, Universidad Autónoma de Bucaramanga. Foscal Internacional, Floridablanca, Santander.
Español Español, Universidad Autónoma de México
Médico especialista en Hematopatología, Universidad Autónoma de México.
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Copyright (c) 2025 Katty Camila Anaya Reyes, Angelica Patricia Araujo Reyes, Jorge Andres Garcia Vera
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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