Bullous pemphigoid related with a cutaneous squamous cell carcinoma, an unusual association
DOI:
https://doi.org/10.29176/2590843X.1971Keywords:
squamous cell carcinoma, Neoplasms, Bullous pemphigoid, skin ulcer, BlisterAbstract
Bullous skin diseases share a complex physiopathology and some of them are associated with an immune response against basal membrane and intercellular junction molecules antigens. Bullous pemphigoid is the most common autoimmune bullous disease, clinically it can be found rapid onset tense blisters in adult patients. We present the case of a 71 yo man with a long onset skin ulcer related to venous insufficiency who developed generalized urticarial plaques and tense blisters without finding any primary tumor other than a squamous cell carcinoma located in the described ulcer.
Author Biographies
Eine Yesid Benavides Tulcán, Universidad del Valle, Cali, Colombia
Residente, Programa de Dermatología, Hospital Universitario del Valle, Cali, Colombia.
Jeyson Montero Castaño, Universidad del Valle, Cali, Colombia
Residente, Programa de Dermatología, Hospital Universitario del Valle, Cali, Colombia.
Claudia Juliana Diaz Gomez, Universidad del Valle, Cali, Colombia
Jefe, Sección de Dermatología, Departamento de Medicina Interna, Universidad del Valle, Cali, Colombia.
References
Miyamoto, D. et al. Bullous pemphigoid. Anais brasileiros de dermatologia. 2019; 94(2), 133–146. https://doi.org/10.1590/abd1806-4841.20199007
Moro, F. et al. Bullous Pemphigoid: Trigger and Predisposing Factors. Biomolecules. 2020; 10(10), 1432. https://doi.org/10.3390/biom10101432.
Schmidt, E. et al. Pemphigoid diseases. Lancet. 2013; 381(9863), 320–332. https://doi.org/10.1016/S0140-6736(12)61140-4
Balestri, R. et al. Malignancies in bullous pemphigoid: A controversial association. The Journal of dermatology. 2016; 43(2), 125–133. https://doi.org/10.1111/1346-8138.13079
Atzmony, L. et al. Association of bullous pemphigoid with malignancy: A systematic review and meta-analysis. Journal of the American Academy of Dermatology. 2017; 77(4), 691–699. https://doi.org/10.1016/j.jaad.2017.05.006
Lucariello, R.J. et al. Association between bullous pemphigoid and malignancy: A meta-analysis. Australas J Dermatol. 2018; 59: 253-260. https://doi.org/10.1111/ajd.12764
Reich-Schupke. et al. Squamous cell carcinomas in chronic venous leg ulcers. Data of the German Marjolin Registry and review. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology. 2017; 13(10), 1006–1013. https://doi.org/10.1111/ddg.12649
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Copyright (c) 2025 Eine Yesid Benavides Tulcán, Jeyson Montero Castaño, Claudia Juliana Diaz Gomez
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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