HTLV-1 associated adult T-cell lymphoma

Authors

  • Lucía Giraldo
  • Santiago Ariza
  • Rocío Orduz
  • Fernando Palma

DOI:

https://doi.org/10.29176/2590843X.312

Keywords:

Human T-lymphotropic virus 1, antiretroviral therapy, highly active, interferon-alpha, lymphoma, T-cell, cutaneous, serology, drug therapy, combination

Abstract

The adult T-cell lymphoma is a peripheral T-cell neoplasm caused by the human T-cell lymphotropic virus, type 1 (HTLV-1), endemic in Colombia. We present the case of a 66 years-old male patient who presented with skin lesions in trunk and extremities. The pathology study established the diagnosis of peripheral T-cell lymphoma NOS (not otherwise specified). Local management of skin lesions started, but it progressed, so adult T-cell lymphoma was suspected and confirmed. 
Colombia is an endemic country for HTLV-1. Dermatologists should be familiar with this malignancy and its different skin manifestations, occasionally simulating mycosis fungoides, in order to identify more cases in a timely manner. 

Author Biographies

Lucía Giraldo

Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, D.C., Colombia

Santiago Ariza

Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, D.C., Colombia

Rocío Orduz

Clínica Universitaria Colombia, Clínica Colsanitas, S. A., Grupo de Investigación, INPAC, Bogotá, D.C., Colombia

Fernando Palma

Clínica Universitaria Colombia, Clínica Colsanitas, S. A., Grupo de Investigación, INPAC, Bogotá, D.C., Colombia

References

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Marchetti MA, Pulitzer MP, Myskowski PL, Dusza SW, Lunning MA, Horwitz SM, et al. Cutaneous manifestations of human T-cell lymphotrophic virus type-1-associated adult T-cell leukemia/lymphoma: A single-center, retrospective study. J Am Acad Dermatol. 2015;72:293-301.

https://doi.org/10.1016/j.jaad.2014.10.006

Mirvish JJ, Pomerantz RG, Falo LD, Geskin LJ. Role of infectious agents in cutaneous T-cell lymphoma: Facts and controversies. Clin Dermatol. 2013;31:423-31.

https://doi.org/10.1016/j.clindermatol.2013.01.009

Nasr R, El Hajj H, Kfoury Y, de Thé H, Hermine O, Bazarbachi A. Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects? Viruses. 2011;3:750-69.

https://doi.org/10.3390/v3060750

Medina EA, Orduz R, Morales OL, Martínez Ó, Baldión M, Isaza MA. Adult T-cell leukemia/lymphoma in HTLV-1 infected patients: Report of two cases in Colombia. Biomédica. 2013;33:519-25.

https://doi.org/10.7705/biomedica.v33i4.1429

Molina A, Molina V, Arroyave J. Linfoma de células T del adulto por HTLV1 con compromiso cutáneo. Reporte de caso. Rev Asoc Colomb Dermatol. 2011;19:167-71.

How to Cite

1.
Giraldo L, Ariza S, Orduz R, Palma F. HTLV-1 associated adult T-cell lymphoma. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jul. 1 [cited 2026 Mar. 17];25(3):232-6. Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/312

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Published

2017-07-01

How to Cite

1.
Giraldo L, Ariza S, Orduz R, Palma F. HTLV-1 associated adult T-cell lymphoma. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jul. 1 [cited 2026 Mar. 17];25(3):232-6. Available from: https://revistaasocoldermaorgco.biteca.online/index.php/asocolderma/article/view/312
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