HTLV-1 associated adult T-cell lymphoma
DOI:
https://doi.org/10.29176/2590843X.312Keywords:
Human T-lymphotropic virus 1, antiretroviral therapy, highly active, interferon-alpha, lymphoma, T-cell, cutaneous, serology, drug therapy, combinationAbstract
The adult T-cell lymphoma is a peripheral T-cell neoplasm caused by the human T-cell lymphotropic virus, type 1 (HTLV-1), endemic in Colombia. We present the case of a 66 years-old male patient who presented with skin lesions in trunk and extremities. The pathology study established the diagnosis of peripheral T-cell lymphoma NOS (not otherwise specified). Local management of skin lesions started, but it progressed, so adult T-cell lymphoma was suspected and confirmed.
Colombia is an endemic country for HTLV-1. Dermatologists should be familiar with this malignancy and its different skin manifestations, occasionally simulating mycosis fungoides, in order to identify more cases in a timely manner.
Author Biographies
Lucía Giraldo
Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, D.C., Colombia
Santiago Ariza
Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, D.C., Colombia
Rocío Orduz
Clínica Universitaria Colombia, Clínica Colsanitas, S. A., Grupo de Investigación, INPAC, Bogotá, D.C., Colombia
Fernando Palma
Clínica Universitaria Colombia, Clínica Colsanitas, S. A., Grupo de Investigación, INPAC, Bogotá, D.C., Colombia
References
Ishitsuka K, Tamura K. Human T-cell leukaemia virus type I and adult T-cell leukaemia-lymphoma. Lancet Oncol. 2014;15:e517-26.
https://doi.org/10.1016/S1470-2045(14)70202-5
Marchetti MA, Pulitzer MP, Myskowski PL, Dusza SW, Lunning MA, Horwitz SM, et al. Cutaneous manifestations of human T-cell lymphotrophic virus type-1-associated adult T-cell leukemia/lymphoma: A single-center, retrospective study. J Am Acad Dermatol. 2015;72:293-301.
https://doi.org/10.1016/j.jaad.2014.10.006
Mirvish JJ, Pomerantz RG, Falo LD, Geskin LJ. Role of infectious agents in cutaneous T-cell lymphoma: Facts and controversies. Clin Dermatol. 2013;31:423-31.
https://doi.org/10.1016/j.clindermatol.2013.01.009
Nasr R, El Hajj H, Kfoury Y, de Thé H, Hermine O, Bazarbachi A. Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects? Viruses. 2011;3:750-69.
https://doi.org/10.3390/v3060750
Medina EA, Orduz R, Morales OL, Martínez Ó, Baldión M, Isaza MA. Adult T-cell leukemia/lymphoma in HTLV-1 infected patients: Report of two cases in Colombia. Biomédica. 2013;33:519-25.
https://doi.org/10.7705/biomedica.v33i4.1429
Molina A, Molina V, Arroyave J. Linfoma de células T del adulto por HTLV1 con compromiso cutáneo. Reporte de caso. Rev Asoc Colomb Dermatol. 2011;19:167-71.
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