Lesions of leprosy reverse reaction mimicking keloids
Keywords:
dyskeratosis, acantholysis, vulvar pathology.Abstract
Leprosy is an infectious disease, curable, and capable of generating deformity and disability, if not diagnosed and treated early. About 20 to 50 % of patients present reactions during the course of the disease, more frequent after treatment has been initiated. Type 1 reaction, or leprosy reverse reaction, occurs mainly in patients with dimorphous-tuberculoid, dimorphous and dimorphous-lepromatous leprosy. We report the case of a 52-year-old male patient, who came to the leprosy outpatient clinic at ASA-FIOCRUZ in Rio de Janeiro (Brazil), presenting exuberant and painful skin lesions, associated with myalgias, systemic symptoms and pa-restesias in the extremities. After the anamnesis and physical examination, it was possible to identify these lesions as an atypical clinical form of type 1 reaction, which was later corroborated with the help of paraclinical studies and the resolution of the clinical picture in the treatment established for leprosy and reactive state.
Author Biographies
Laura Sofía Habib
Médica, residente de tercer año de Dermatología, Instituto de Pós-Graduação Médica Carlos Chagas-Policlínica Geral do Rio de Janeiro, Rio de Janeiro, Brasil.
Fred Bernardes-Filho
Médico dermatólogo, Pontifícia Universidade Católica do Rio de Janeiro, Rio de Janeiro, Brasil; Instituto de Dermatología Professor Rubem David Azulay-Santa Casa da Misericórdia do Rio de Janeiro, Brasil.
Raquel Cristina Maia
Médica dermatóloga. Hospital Mário Kröeff-Instituto de Pós-Graduação BWS, Rio de Janeiro, Brasil.
José Augusto da Costa Nery
Médico dermatólogo, magíster en Dermatología, doctorado en Enfermedades Infecciosas y Parasitarias; jefe, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz; jefe, Sector de Dermatología Sanitaria Instituto de Dermatologia Professor Rubem David Azulay-Santa Casa da Misericórdia do Rio de Janeiro, Brasil ; professor titular, Universidade Estácio de Sá; profesor asociado, Policlínica Geral do Rio de Janeiro, Rio de Janeiro, Brasil.
Ana Maria Sales
Médica dermatóloga, magíster en Dermatología, doctorado en Epidemiología; investigadora asociada del Ambulatorio Souza Araújo, Fundación Oswaldo Cruz, Rio de Janeiro, Brasil
Alice Miranda-Machado
Médica patóloga, doctora en Biología Parasitaria, Laboratorio de Lepra; investigadora asociada, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz, Rio de Janeiro, Brasil.
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